วันอาทิตย์ที่ 21 ธันวาคม พ.ศ. 2551

BioAsia 2007

BioAsia 2007: Opportunities for scientists to meet with peers and funding agencies


Bangkok, Thailand - The National Center for Genetic Engineering and Biotechnology (BIOTEC) – Over 30 scientific presentations and over 100 trade exhibitors will be presented at BioAsia 2007 Thailand, which will be held during 5-9 November 2007 at Queen Sirikit National Convention Center, Bangkok, Thailand (www.bioasia-2007.com). BioAsia 2007 Thailand aims at bringing together agricultural scientists to share research experiences. In addition, the event will also provides opportunities for scientists to schedule private, pre-arranged one-on-one meetings with peers and funding agencies.

“Multidisciplinary Approaches to Better Understand the Genetic Basis of Drought Tolerance in Plants”
By Dr. Jean-Marcel Ribaut, Generation Challenge Programme, C/O CYMMYT, Mexico

Dr. Jean-Marcel Ribaut is an internationally acclaim expert in the field of drought tolerance. He has been in charge of genetic dissedtion and marker-assisted selection (MAS) for maize and wheat improvement under abiotic stress condition and development of new MAS strategies. He is currently Director of the Generation Challenge Programme, a research and capacity building network that uses plant genetic diversity and advanced genomic science to develop tools and technologies that enables plant breeders in the developing world to produce better crop varieties for resource-poor farmers.

Recently, we caught up with Dr. Ribaut to ask him about his upcoming talk at BioAsia 2007 in Bangkok, Thailand.

What is/are the highlight(s) of your speaking topic?

The talk will focus on the need for, and benefits of, an interdisciplinary approach to understanding genetic control and identifying genes involved in the expression of complex, polygenic traits like drought tolerance. The point is that each approach (functional genomics, Quantitative Trait Loci analysis, metabolomics, etc) by itself provides useful information, but it is only one piece in a complex set of information: only an integrative approach will help identify regulatory genes and reveal how genes interact in response to environmental conditions. It is also equally important to realise that the discovery phase has to be followed by a validation phase, which involves testing the genetic effects of selected genes under target environments using adapted germplasm, in order to develop tools/markers that will impact plant breeding for polygenic trait.

As an international and interdisciplinary initiative aiming to develop and utilise genomic resources to enable plant breeders in the developing world produce better crop varieties for resource-poor farmers, a description of the Generation Challenge Programme (GCP) will be presented as a detailed case study. GCP links basic research with applied science, by generating useful knowledge and developing practical tools such as molecular markers for target traits to complement phenotypic selection and impact crop breeding for adapted germplasm in target environments. Marginal drought-prone environments are a key focus for GCP.

What will the participants gain from attending your speaking session?

Participants will understand how to organize scientific projects to identify genes involved in the expression of polygenic traits of agronomic importance, such as drought tolerance. They will be exposed to the limitations, challenges and strengths of using biotechnologies as discovery tools. Several practical examples will be presented for participants to appreciate the power of combining marker-assisted selection with phenotypic selection.

Participants will also be exposed to the Generation Challenge Programme of the Consultative Group on International Agricultural Research (CGIAR). GCP is a broad international and interdisciplinary network of partners collectively working to improve crop productivity in drought-prone environments.

Scientific Poster Awards (Rice and Crop Science)

The Poster Award Committee will present two Poster Awards, one for work on rice and the other on crop science, to the outstanding scientific abstracts and posters. Each winner will receive a cash prize of USD 500, courtesy of BIOTEC. In addition, each winner will also receive two books of his/her choice with a total value of not more than US$200. The book award is made possible by John Wiley & Sons and the selection is based on the books available at Wiley's website www.willey.com

BIOTEC opens Microbe Bank to provide micro-organisms

BIOTEC opens Microbe Bank to provide micro-organisms for research and commercial applications


• Pushing Thailand as a regional centre for tropical microbiology
• World class microbe bank stores microbes collected over more than ten years with the most diverse selection of insect-pathogenic fungi in the world
• More than 100 researchers are available to consult and transfer knowledge to the private sector
• Commercially applicable results can reduce R&D time and costs
Bangkok (28 September 2007) – BIOTEC/NSTDA are supporting Thailand’s quest to become a biotechnology leader by launching a new service of providing samples of many different strains of micro-organisms collected in a Microbe Bank. Experts will transfer technology to the private sector, helping strengthen Thai industries and increase Thailand’s competitiveness in global markets.

Prof. Dr. Morakot Tanhcharoen, Executive Director of the National Genetic Engineering and Biotechnology Center, or BIOTEC, under the National Science and Technology Development Agency (NSTDA), said, “To support the widespread application of biotechnology BIOTEC has now opened a Microbe Bank for students, researchers, and companies that want to obtain micro-organisms for research or for commercial applications. This service will give people a reliable source of high quality samples and will reduce the time spent on searching for and studying microbes so that people can obtain the existing strains and put them to use more quickly. We want Thailand to be the regional centre for tropical microbiology research.”

“Thanks to the diversity of our geography, Thailand is a very rich source of more than 200,000 kinds of algae, bacteria, fungi and yeasts. Researchers as BIOTEC have been collecting and storing samples of these micro-organisms for over ten years so BIOTEC’s Microbe Bank has a more diverse collection of microbes than any other in the region, especially our collection of fungi that cause diseases in insects. It is the most diverse collection in the world. There are more than 400 types of fungi that can destroy insects that were found in Thailand and we have isolated and keep active cultures of over 4,000 strains at the Microbe Bank,” said Dr. Somsak Sivichai, a researcher.

Wanchern Potacharoen, Manager of the Microbe Bank, said that the bank was ready to provide services with a large amount and diverse range of quality microbe samples. They are arranged, stored, and managed under the same standards as those of microbe banks in the USA, Europe and Japan.

Researchers at BIOTEC have studied these diverse strains of microbes and tested them for different applications in medicine, agriculture, the food industry and environmental management to reduce dependence on chemicals and imports of medicine and other products as well as to improve agricultural products and create added value so that Thai products can better compete in the world market.

The Microbe Bank manager said, “BIOTEC wants to support broad collaboration in the study of microbiology so we are providing storage services and sample services. Some of the services are free and for others we charge a modest fee that is 5-10 times cheaper than at other microbe banks in Europe or America. We also created a cooperative network with two other national agencies that maintain microbe cultures: the Agriculture Department under the Ministry of Agriculture and Cooperatives (MoAC) and the Medical Science Department under the Ministry of Public Health (MoPH). BIOTEC is the secretary of the network. The purpose is to exchange knowledge and research results.”

She continued, “BIOTEC employs more than 100 researchers who are working to find ways to apply microbiology in industry, agriculture, environmental management and medicine. They are available to provide advice and training and to collaborate in research with people from the private sector in order to produce marketable products. Some examples are using microbes to speed up the production process for making fermented sausage or fish sauce, or using microbes to convert the cellulose in agricultural by-products like rice bran and sugar cane fibre to make alcohol for a fuel source.”

Assoc. Prof. Dr. Sakarindr Bhumiratana, Director of the NSTDA, said, “The Microbe Bank and the microbiology network will help BIOTEC and other agencies make use of the R&D work that has been going on in order to produce really practical applications for industry, agriculture and medicine. This will lead to more innovations and patents in Thailand to help the nation meet the goals set in the “Fast Forward” plan. It will make Thailand more competitive in discovering and inventing new innovations to create an advantage in production. Greater application of science and technology will lead to a stronger and more sustainable economy.”

BIOTEC’s Microbe Bank has more than 20,000 types of microbes available. They are stored frozen in liquid nitrogen or in vacuum tubes under a system that meets the ISO 9001 standard. Microbiology experts set the storage method and steps in order to insure samples that are viable, true to form and uncontaminated.

NSTDA launches Phase 2 of Thailand Science

NSTDA launches Phase 2 of Thailand Science Park; invests 2 billion baht


• Target set to attract 200 Thai and foreign investors to occupy more than 50 per cent of the space, five times more than at present

• The largest and most comprehensive R&D center in Thailand

• Affirming the ‘Fast Forward’ plan to build alliances and increase the number of patents for new innovations

Bangkok (11 October 2007) – Thailand Science Park, under the management of the Technology Management Center TMC, (a unit within the National Science and Technology Development Agency or NSTDA), announced the launch of Phase 2 with an investment of about two billion baht. The target is to pull in more private sector research and development companies so that they occupy more than half the area of the park.

Phase 2 of Thailand Science Park is located in the same area as Thammasat University’s Rangsit Campus in Khlong Luang District, Pathum Thani. It has 72,000 square metres of usable space and about 40,000 square metres is expected to be sold to private sector R&D companies.

Construction of Phase 2 is to begin in late October 2007 and to be completed in 2010.

Professor Dr. Chachanat Thebtaranonth, Deputy Director of NSTDA, said, “The progress on the Thailand Science Park project has proceeded more quickly than we planned.”

“Phase 1 of the project was intended simply to support the government’s research and development organizations, especially the NSTDA and its centers: BIOTEC, MTEC, NECTEC, NANOTEC and TMC. These organizations were to be the core of the park and a magnet to attract private sector companies to come in and invest in R&D projects in Phase 2. As it turned out, Phase 1 has already advanced farther than we predicted. Companies like Betagro and a subsidiary of Siam Cement are already using about 11,000 square metres in Phase 1. Now we have set a goal of selling more than 50 per cent of the space in Phase 2 to the private sector,” the deputy director said.

Thai scientists at NSTDA and KMITL

Thai scientists at NSTDA and KMITL invent breakthrough nano crystal 'detection' eyeglasses


• Prototype glasses can help in crime detection work; presented to forensic experts for crime scene investigations

• Homegrown Thai innovation applied U.S. patent

• Single set of nano-glasses help detectives see ‘invisible’ bodily fluids left behind at crime scenes

• Nano-crystal research to be expanded into medicine and agriculture

Bangkok – Thai scientists have developed a unique pair of nano-crystal eyeglasses to assist forensic specialists in their work. A single pair of nano-crystal glasses can help crime scene investigators see ‘invisible’ traces of bodily fluids such as blood, saliva, lymph, and sperm left behind at the crime scene. The prototype was presented today (25 October) to the Central Institute of Forensic Science for use in its crime scene investigations. Further research is being planned to expand the nano-crystal technology applications to the medical and agricultural sectors.

The invention is the collaborative achievement of a team of scientists from the National Science and Technology Development Agency (NSTDA)’s nanotechnology centre (NANOTEC), the National Electronics and Computer Technology Center (NECTEC), as well as King Mongkut’s Institute of Technology Ladkrabang (KMITL)’s Nanotechnology Research Center.

Dr. Teerachai Pornsin-Sirirak, Deputy Director of NANOTEC, said, “Nano-crystal eyeglasses are an important by-product of our research into nano-crystal. It has already been submitted to the patent offices of the United States and we are exploring the possibility for commercialization and mass production of the product.”

According to Dr. Teerachai, the innovation is in line with NSTDA’s Fast Forward plan to accelerate the number of patents for Thai inventions.

He cited that nano-crystal is an important by-product of the agency’s active research on nano thin film for deployment in nano electronics to produce solar cells, photo detector and LED (Light Emitting Diode).

“We strongly believe that there are a lot more wonderful discoveries to be made from our research work – the discovery of nano-crystal and its applications being one of them – that is good for the Thai society. This is a very good example of balancing long-term research with immediate benefits. We are conducting fundamental research that can yield benefits to Thailand for the long-term. However, we are also being commercially minded in terms of finding immediately useful applications from our on-going research work,” said Dr Teerachai.

Associate Dr. Jiti Nukaew, Director of the Nanotechnology Research Center, KMITL, who leads the nano-crystal eyeglasses project, said that nano-crystal is obtained by applying nano crystallized indium oxynitride onto glass or plastic lenses. The result is a special lens capable of filtering varying wavelengths of light. Nano-crystal eyeglasses work as a filter to keep out blue, green and red light as well as ultraviolet rays, including UV-A, UV-B and UV-C. The special eyeglasses are also easy to manufacture using materials that are locally available.

When used in crime scene investigations, nano glasses equipped with nano-crystal lenses allow forensic scientists to detect – with only a single pair of eyeglasses – more than one type of bodily fluid such as blood, saliva, lymph or sperm, making detection work simpler.

Pol. Lt Col Somchai Chalermsooksant, Forensic Scientist and Chief of Crime Scene Unit, Central Institute of Forensic Science, said that in crime scene studies, particularly in rape or murder cases, forensic specialists often look for bodily fluids as evidence. UV rays are projected onto the areas where such fluids could have been left behind. In the fluids, there are proteins that react to UV light.

To detect these, investigators need to wear customized eyeglasses that operate under three different colours: yellow, orange and red. Each colour works to block out light with a different wavelength. At the moment, scene investigations take up a lot of time since the same detection process must be conducted multiple times with each different wavelength of projected light and glasses appropriate for each type of fluid. “Now, we can just wear one pair of Thai-made nano-glasses and do everything in one step,” he said.

Pol. Lt Col Somchai added, “Nano-crystal eyeglasses are truly innovative, and demonstrate how the use of nanotechnology can benefit society by supporting our forensic teams in their mission. With this device, information on bodily fluids left at crime scenes can be obtained faster. The low-cost Thai-made product will also mean this technological benefit will now be accessible to a lot more people and government units.”

Besides its forensic application, nano-crystal eyeglasses can be developed for specialists administering UV rays in medical or cosmetic treatments, and for practitioners performing laser surgery. It can also be used as a protective device for metal welders as well as for staff sorting black tiger prawns.

After presenting the pair of nano-crystal eyeglasses to the Central Institute of Forensic Science, the research team will provide nano-crystal eyeglasses for tests trials use in other industries. The field tests are expected to be completed in early 2008.

Engineers to come from collaboration

Engineers to come from collaboration


To train people in science and technology, the Science Ministry has established Thailand Advance Institute of Science and Technology as a center for collaboration amongst universities and research institutions within and outside the country. Called ThaiST for short, the institute was set up under a consortium model to link research centers in Thailand with local and international universities to develop courses in particular fields, said Yodhathai Thebtaranonth, an adviser to the Science Minister.

Set up this year, ThaiST has created the first collaboration between two Thai universities, King Mongkut Institute of Technology at Lad Krabang and Sirindhorn International Institute of Technology, as well as the National Metal and Materials Technology Center (MTEC) to develop a master’s degree course on automotive engineering. The course is also supported by the Tokyo Institute of Technology.

“This is the first master’s degree course and it was launched in June this year. We hope this course will be a starting point for the institute to develop collaboration to move into other field,” he said.

The collaboration with research institutes will allow students the chance to use laboratory facilities to do their research, while researchers in the lab could also train students for further research development. In the first stage, the automotive engineering course is expected to produce around 20 master’s degree automotive engineering for the country.

As the automotive industry is one of the country’s key strategic weapons, it requires more people in particular fields to work for the industry. Local universities do not yet have this kind of course to train people to meet the demand. Yodhathai said it is the institute’s duty to see demand in the market and train people to serve that demand.

Apart from automotive engineering, he said examples of other fields which the institute planned to develop include biotechnology, geo informatics, nuclear technology, and cosmetic science.

As a chair professor, Yodhathai said those who received scholarships would have to do their research projects to serve the country while training others in the field. The project will also serve the ThaiST’s training mission since the chair professor will also help the institute develop courses, Yodhathai said. The ministry has also talked with the private sector on the idea and it has received support from the private sector to offer scholarships.

In the process, the ministry will set up a committee to select qualified scientific researchers to become chair professors and after two years, the chair professors will be evaluated by another committee.

Cutting-edge technology

Cutting-edge technology


Morakot Tanticharoen, a director of BIOTEC, aims at greater public understanding of the science she says can do so much for Thailand

One of the leaders in the complex and controversial world of biotechnology in Thailand is a woman who has spent 35 years in the study of biology and microbiology.

Morakot Tanticharoen, a director of the National Centre for Genetic Engineering and Biotechnology (BIOTEC), has a goal of creating wider understanding of her science, particularly among farmers, whom she says could benefit greatly from advances in biotechnology. In the beginning, however, Morakot had no idea she would become a biotechnologist, and her career began as a kind of shot in the dark.

"When I was young and a teenager, I had no plan to become a biotechnology scientist, but I liked mathematics, so I applied to study biology," she says.
Morakot admits that during her time at Chulalongkorn University she was not an excellent student. Fortunately, she had a good memory that enabled her to remember lessons or gather facts from a single reading of a book. She spent much of her university life engaged in student activities and became president of female students in her faculty's Biology Association.

"I liked those kind of activities and I dedicated my time to that at university. I enjoyed it; it made me happy," Morakot says.

As a student leader, she learned how to manage her time to keep up with her studies. But she quickly proved her effectiveness as a leader. Her association's team won three out of four trophies for various campus activities.

"I was leading people for the first time in my life. I did not set out to be president of the students. A friend asked me to go along with her because she was one of the candidates. When I got there, someone submitted my name as a candidate for the presidency," she recalls.

Morakot graduated from Chulalongkorn with a bachelor's degree in biology in 1968. She then applied to work as a researcher before studying for her master's and doctoral degrees in the US. Morakot was appointed as a research assistant at the University of Rhode Island, where she completed her postgraduate studies. Upon her return to Thailand, Morakot was offered the position of biotechnology professor at King Mongkut's Institute of Technology Thonburi (now King Mongkut's University of Thonburi, or KMUTT), where she founded the School of Energy and Materials. The school teaches at graduate level and conducts research involving multidisciplinary technologies.

Morakot is an acknowledged leader in teaching and researching energy generated from biomass, biomass production, the energy balance of biomass production, bioproductivity and bioleaching. Within the School of Energy and Materials, Morakot later founded the Division of Biotechnology, which was subsequently transformed into the School of Bioresources and Technology. The curriculum has been expanded to include the Division of Biotechnology, natural resources management, postharvest technology and biochemical technology.

In more than two decades at KMUTT, Morakot served as Dean of the School of Bioresources and Technology as well as the School of Energy and Materials. In doing so, she has been as an adviser or co-adviser to more than 100 postgraduate theses and dissertations.

Morakot says that as dean she was not only a teacher and team leader but also provided support for students and staff studying or conducting research overseas, so that they would become experts in their fields and return to Thailand to help develop the country.

"We realised that work as team was very important. We had a heavy workload and enjoyed doing it. We also believed that if we concentrated and focused on our work, then it would be successful," she says.

Morakot is now one of Thailand's leading researchers in the fields of microbiology and biotechnology. Her specialities include anaerobic wastewater treatment for biogas production and studies of algae. She is also a pioneer in biosensor research in Thailand. She is also recognised for her involvement in regional and international research, and is an executive member of several societies and organisations, as well as serving on the editorial board of a number of noted international journals. While Morakot has been a director, BIOTEC has been appointed executive secretary of the Unesco Regional Network for Microbiology and Microbial Biotechnology in Southeast Asia. Morakot herself heads up an Asean subcommittee on biotechnology.

Before being appointed a director of BIOTEC, Morakot was a deputy director for six years, from 1994 to 2000. When appointed as Biotec's first female director in 2000, she saw her responsibility as creating and developing new biotechnologies to improve Thailand's productivity.

"I have been working at BIOTEC for 12 years," she says. "I believe that biotechnology is a growth dynamic for this country and that Thai researchers have the potential to lift Thailand's productivity and international competitiveness." She also believes that farmers should benefit from biotechnology to enhance their business and productivity and to add value to their products. She mentions the creation of seed production industries in Thailand as one way in which biotechnology can help farmers. A seed-production industry could serve both the domestic and international markets for crops such as sweet corn, chillis, tomatoes and cucumbers, she says.

"We are trying to step forward and cooperate with the private sector as members of a Thai team, to transfer technology and undertake research to develop, promote and create value for new products based on biotechnology, as a strategy for the country," Morakot says.

The biotechnologist is also eager that the public - and particularly children - should have a greater understanding of her science. She has proven to be an able author, transferring her knowledge in books such as "Biodiversity and the World of Microbes".

"I like to read books and I also enjoy writing science books for children so that they are able to easily understand the science and technology that is becoming a larger part of their environment," Morakot says.

Super khao hom coming

Super khao hom coming


Thai researchers at the National Center for Genetic Engineering and Biotechnology (BIOTEC) are developing a breed of fragrant jasmine rice that is resistant to pests and diseases, as well as to flash floods, drought and salinity, the Science and Development Network reports.

The ongoing research, which uses laboratory techniques to back up traditional breeding methods, was presented at the international BioAsia 2007 conference in Bangkok earlier this month, according to the SciDev.net article.

Thailand is the world's largest rice exporter, with jasmine rice the most popular. But the country's rice plants often have to struggle against severe flooding or drought, as well as damage by the brown plant hopper (BPH) and bacterial leaf blight (BLB).

The experimental rice withstands nearly three weeks of flooding and is resistant to BPH and BLB, says Apichart Vanavichit, director of the Rice Gene Discovery Unit in Thailand, who is leading the research. His team is now looking for genes that enable other rice plants to tolerate salt conditions and drought.

Vanavichit said they hope to release their "super rice" with the whole set of resistance genes by 2012.

The scientists use genetic marker techniques to locate the desired genes in different rice varieties, which helps them identify the best parent plants for breeding.

Work began in 1998 with the identification of flood-resistant genes in a local Indian rice variety.

In 2001 the researchers conducted a field trial, and last year gave the flood-resistant rice seeds to farmers in northern Thailand.

Meanwhile, researchers crossbred plants with BPH- and BLB-resistant genes from a wild Sri Lankan rice and samples from the International Rice Research Institute (IRRI), before combining those traits with the flood-resistant jasmine rice.

"What would happen if India hadn't allowed us to use its rice variety? The sharing of genetic resources is definitely beneficial," said Vanavichit.

Surawit Wannakrairoj, a member of the Thai National Plant Variety Committee, told SciDev.Net that the results showed that Thailand does not need to embrace genetic- modification biotechnology.

Duncan Macintosh, a spokesperson for IRRI, says the development of flood-resistant rice is progressing well in several countries, so the chances of success in Thailand are high. "But the main challenge will be to maintain the quality of jasmine rice," he told SciDev.Net

NECTEC software

NECTEC software will help to improve speech


New software to enable patients suffering from cero-brovascular disease and autism to communicate normally has been developed by Mahidol University’s Siriraj Hospital and the National Technology Center (NECTEC).

NECTEC director Dr Pansak Siriruchatapong said the programs would help an increasing number of patients with speech impairments, including those who suffered from autism, deafness, or have had a stroke.

NECTEC researchers spent 15 months developing he software. “I hoe patients will be happy to be able to talk and express their feelings to others,” Pansak said.

NECTEC has developed three software programs – a Thai speech assessment program, a program to control the quality of voice and language, and an electronic device that can help patients admitted to Intensive Care Units (ICU) to communicate with physicians and visitors.

Speech therapists and physicians could use all the three programs to help ad train their patients to communicate with others, he said. The Thai speech assessment is designed for therapists to evaluate the speech capabilities and voice quality of the patient.

They would be trained to pronounce the word and express their voice into the computer, which would then read the patient’s tone of voice, time, and rhythm to express the word. The program would then record the result and report the progress of training to the speech therapist, and allow them to evaluate and improve the patient’s skill.

The other computer program called “Prasai” will be used to help patients who have lost the ability to communicate due to autism or after suffering a stroke. This program will be used to help patients boost their memory by using multimedia information, including pictures, synthetic voices and text to recognize words and sentences.

“The program will show a picture or image on the computer screen and the patient would hear the synthetic voice when they place a finger on the touch screen. If they train every day, their memory would improve,” he said.

The last program, called “ICU Talk”, is designed for patients admitted to ICUs who are unable to communicate with others. Patients will use touch screen or a button to control the command, and then the computer will express the synthetic voice enabling them to communicate with doctors or family members.

Siriraj Hospital Director Dr Piyasakol Sakolsatayatorn said the hospital would select 30 in-patients to join a one-year trial to evaluate the implementation of these programs, and Nectec will then improve the program accordingly. He said the three programs were expected to be provided to other hospitals and institutes next year.

Archives going digita

Archives going digital


Thailand will soon have a huge set of digital archives which will include all Thai-based data in every field and allow people at all levels to get access to an enormous amount of knowledge any time.

That's a mission for the National Electronics and Computer Technology Centre (NECTEC), which plans to transform all physical data scattered around the nation into digital form.

The centre has initiated a new project called Digitised Thailand to develop the national digital content, which can be used to improve knowledge, preserve culture or even make new business developments.

NECTEC's director Pansak Siriruchatapong said Digitised Thailand would be the centre's flagship project to integrate a variety of technology-development projects at NECTEC to build the country's largest digital archive collection for practical use.
The project is part of the centre's plan to utilise information and communications technology to lay down the country's intellectual infrastructure to improve literacy and develop Thailand towards a knowledge-based society.

A team at NECTEC is working to develop the Digitised Thailand framework as a guideline for the country and all parts of society when they collect data in digital format.

Virach Sornlertlamvanich, information and mobile application programme manager at NECTEC, who is also the project leader, said the project, which would run for three years, would start by collecting all Thai data available on the Internet into an archive. Meanwhile, the team would begin to select useful content and convert the physical data into digital form.

"Now we have started the data-collection process and we chose to digitise content about Thai herbs first," he said.

As there is a large amount of information scattered around the country, in the first stage the team has to convert selective data into practical information.
To digitise Thailand, Virach added that it was necessary to encourage all parts of society to collect content in digital form.

NECTEC also plans to develop a framework for digital data collection so it can all be stored using the same standard and this would facilitate information exchange across the network.

"After we begin to digitise data about Thai herbs, we will encourage people and organisations, especially libraries, to turn their physical data into digital form. Once everyone can make their own digital content and put it on the Internet, we will have an enormous database which can be developed into sustainable knowledge," he said.

For Virach, digitised information can be anything from academic knowledge, history, cultural information, travel, technology through to entertainment, so as the large digital archive offers useful knowledge and real information, technologies to help its management are required.

He said that since the project was related to collecting a large amount of data and managing a huge database, the team had to integrate various kinds of technology to build the national digital archive.

Human language technology including a Web crawler to collect data, and a smart search engine, will bring information scattered in many places to users as required. Knowledge-engineering technology also plays an important part in building and maintaining knowledge-based systems.

Large database management systems are another important part of managing the overall database.

Virach said that other technologies used in the project included networking, security and information and mobile applications. All would facilitate access, search and delivery of useful information to users.

To make the information access support any kind of device, NECTEC also plans to develop a standard application program interface (API) to allow users to access all digital content from all kinds of terminals.

"We foresee that the implementation of the national digital archive will be a showcase to turn research and development work done at NECTEC into practical use. This will be our flagship to make Thai-developed technologies come out commercially," he said.

Virach hopes that the project will benefit the business sector. Since a huge amount of digital data is provided for free, he said businesses could use this digital content to make further development for future information services.

As part of Digitised Thailand's plan, NECTEC is now working with the Science and Technology Knowledge Centre at the Science Ministry to develop an electronic forum as a centre to publicise local research work.

The forum will be a centre where researchers can publicise their work and propose their development projects while research-funding organisations could see projects with potential to provide support.

Since the electronic forum will gather research and development and profiles from local researchers, it can be used as the country's research database for further development.

Virach said the government could use this research database to develop policy and set a direction for the country's R&D.

Nation First: Secret of Managing NSTDA

Nation First: Secret of Managing NSTDA?s talents


Right now, the challenge for a national-level organization like the National Science and Technology Development Agency (NSTDA) is not just how to efficiently apply the nation’s advanced science and technology capabilities to the fields of industry, agriculture and medicine to propel Thai economy to the world arena. In addition, this organization needs to take care of the nation’s top brains and make sure they can all work together happily.

It is not easy to manage people who are among the nation’s leading minds. Thus, NSTDA has divided its duties into five major centers. First, there is BIOTEC, working in biotechnology developments. Next is MTEC in charge of materials technology. NECTEC is working on electronics and computer technology developments. The fourth center is NANOTEC, working in nanotechnology, and the fifth is TMC, in charge of helping researchers and companies apply research results for commercial projects. In order to make the work as efficient as possible, all the people at these five centers have to be prepared to work together and coordinate projects quickly.

At first, NSTDA chose “Fast Forward” as its theme to express the concept of the unified mission that all the agencies have to work towards together. The scientists and experts in all different fields are all working as part of NSTDA family.

Dr. Narong Sirilertworakul, Deputy Director of NSTDA, talked about the organization’s great task. From now on, Thailand has to try to invent and create its own technology and adapt ideas from other places to make them even better. This will create lasting stability for the nation. The people at NSTDA need to know and understand the needs of the country in different situations so they can ask the right questions when doing research and get results that are really useful in meeting those needs.

“First, you have to look at the needs of the country, the needs of rural communities, the needs of the people, the people’s quality of life. When you’ve identified those needs, then you set them as the questions and see how NSTDA’s or other researches going on in the country can answer them and how it can strengthen the related industries.”

You have to admit that since there are over 2,000 very diverse and very capable people working at NSTDA, it is not easy to meld them together. They are all master’s degree or PhD holders. To guide them all to work in the same direction, NSTDA has set five core values as the common focal points.

Let’s look at the NSTDA’s five core values. The first one is “NATION FIRST.” That means people should work for the good of the nation rather than focusing on their own selves. They should work for the common good, with conscience and social responsibility. They should be willing to make sacrifices. This value of “NATION FIRST” is something very important to think about in every part of the work, from setting a budget to proceeding with a research project.

Next is the value of “SCIENCE & TECHNOLOGY EXCELLENCE.” The researchers should strive for excellence in everything they do and do their jobs responsibly to find truly new discoveries. Dr. Narong said, “We always say, at NSTDA there is no such thing as ‘good enough’ or ‘the best we can do’ because we believe everything can be even better, even more accurate, even more useful, even more efficient. People at NSTDA have to constantly develop themselves to keep advancing and changing for the better.”

The third value is “TEAMWORK.” Teamwork requires many things, such as the willingness to listen, two-way communication, and daring to give constructive criticism. Teamwork is essential because the two main things required for science and technology research are money and people, and Thailand has only a limited amount of both. NSTDA researchers need to work together with other researchers at outside organizations and universities, with an eye to address the needs of the nation. Many of the successful projects NSTDA has completed, are the work of both NSTDA researchers and researchers from other agencies.

The fourth core value is “DELIVERABILITY.” NSTDA researchers have to be determined to deliver high quality work according to their promise. Everyone should be quick and flexible and should remain enthusiastic about the work. No matter if the research is a success or a failure, the results should be delivered on time. Sometimes the nation’s needs cannot wait.

The last core value is “ACCOUNTABILITY.” NSTDA puts great emphasis on ethics, morality, transparency and standing up for what is right. The researchers definitely need to have professional ethics and accountability.

Dr. Narong affirms that these five core values are his main strategy for making sure the capable people are moving forward in the same direction. The values make the organization strong. NSTDA always checks to make sure that all the personnel are following the organizational culture. Even if someone leaves the organization, if the organizational culture is deeply ingrained, then the new comer to take his place will soon be socialized to follow the same goals.

If you look at the human resources management of almost any organization in Thailand, you’ll see that they all try to keep their best people working there. However, at NSTDA it is quite the opposite because of its “NATION FIRST” policy. If someone whose work skills were developed at NSTDA moves on to do research for another government organization, a university, or the private sector, it will still be a good thing to help strengthen the nation. It seems funny to hear the NSTDA executives ask “Is our turnover rate too low?” You could say that developing personnel and sending them to work at other organizations is one of the missions of NSTDA.

NSTDA executives are aware that it is not easy to satisfy scientists and keep them working at one place for a long time. “Money may be one factor that attracts scientists to an organization, but even more important is the research environment; the work environment. These people have a unique way of life, their way of thinking and their creativity. NSTDA has to build up a good climate and provide frequent opportunities for free exchange of ideas. We have to give the scientists chances to discuss their work and present their results. They want to attend meetings and conferences to know what’s going on and keep abreast of new technology.”

NSTDA has invested a great deal in IT. The researchers can work 24 hours a day from any location—at home, at the office, or even overseas. They can access all the information they need.

NSTDA coordinates and collaborates with other research organizations in Thailand and other countries. It organizes a conference every year to present the research results of its scientists and to let them exchange ideas with people in different industries. NSTDA scientists frequently make overseas trips to learn about new research techniques.

Another important point is job security. They give all the personnel opportunities to grow both in research and administration.

Dr. Narong said, “Above all else, we have to understand the needs of our people and the needs of the market. We have to understand market competition and learn to adjust ourselves to match the situation.”

This is his strategy for taking care of the country’s top brains. Still, he says it is a continuous challenge for the NSTDA administrators to oversee all the researchers. Not only to they want to push them to use their talents and work as a team, they also want to make sure they put out their best work to answer the needs of the country. They have to try to come out with new innovations, and most importantly, they have to work to spread their knowledge and ideas out to the public. The trick is to keep the researchers working on track according to the organization’s goals while, at the same time, giving them the freedom to think of creative new answers.

Global warming is top science news

Global warming is top science news in 2007


Global warming ranks as Thailand’s top science and technology news in 2007, followed by stem cell developments, according to a survey by the co-operation between the Writers & Publishers Forum and National Science and Technology Development Agency (NSTDA). Associate Prof. Dr. Sakarindr Bhumiratana, NSTDA director, said the survey focused on the interest in science news among 3,000 people in Bangkok and the surrounding areas.

News about global warming ranks top, followed by news on stem cells. Other science and technology news stories of interest include reports of Thai teenagers winning gold medals in Olympiads, Internet threats, robot competitions, the Leonid meteor showers, nuclear power plants, lead-free noodle pots, GMO field trials, and NANO products.

Assoc. Prof. Dr. Sakarindr confirmed that the survey identified a segment of the public that are interested in science issues relating to living and health problems. The stem cell issue for treatment of illness and the support of intelligent students were two excellent examples.

The NSTDA will, in the future, promote science-related news, particularly about industry and product development. It also plans to educate the public regarding more controversial issues such as GMO crop trials and the construction of nuclear power plants.

Varsity adopts biodiesel-B100

Varsity adopts biodiesel-B100


Bangkok University of Rangsit Campus is serving as a model for a green campus they have termed as biodiesel-B100 to fuel the university’s transportation needs.

The campus is also expected to act as a demonstration center for the production of biodiesel from used cooking oil and palm oil from the nearby communities.

The university, with the close cooperation of the National Metal and Materials Technology Center (MTEC) and the Department of Naval Dockyard, early this month set up a system with a maximum capacity to produce 400 liters of biodiesel a day

However, at the intitial stage, it would produce just 100 liters of B100 each day to fuel nine public buses running inside the 441-rai campus. Boonrod Vuthisatkul, vice president of the Rangsit Campus, explained that the university has turned to the more environmentally-friendly fuel because of the rocketing price of other fuels and to fight global warming.

“The fuel price crisis and rising concern over climate change have forced us to do something good for a better environment and lowering our production costs. Biodiesel is the perfect replacement for them,” said Mr. Boonrod.

Currently, the university is buying used vegetable and palm oil at 16 baht a liter of biodiesel out of 100 liters of used cooking oil.

Sountaree Ratapasakorn, a lecturer at the Engineering Faculty who was in charge of the biodiesel project, said the university was confident in the effectiveness of B100 as the Department of Naval Dockyard had previously used it in various types of vehicles, including pick-up trucks, with no engine problems.

“We want to promote public understanding about biodiesel. It is safe for the engine and helps improve the environment by releasing less carbon dioxide emissions into the air. Moreover, we can save heavily on fuel costs as well,” said Ms. Sountaree.

The university will used the biodiesel production system it has loaned from MTEC for another six months before installing its own equipment.

Yongyuth Yuthawong, science and technology minister, expressed his support to the university over the project, saying that it would also help improve the country’s economic health. The Ministry of Energy has forecast that the consumption of fuel this year would go up by 3.2% for benzene or an increase of 7,215 million liters a year from 2006 to 7,483 million liters. Diesel consumption is expected to rise by 2.4% from last year. The use of biodiesel is expected to rise to 1,677 million liters a day, compared to only 0.117 liters last year.

วันศุกร์ที่ 19 ธันวาคม พ.ศ. 2551

NECTEC sets direction for RFID development

NECTEC sets direction for RFID development


To set the direction to develop a radio frequency identification (RFID) industry in the country, the National Electronics and Computer Technology Centre (NECTEC) has developed the first RFID industry road map to encourage the use of RFID technology and stimulate local research and development to serve the emerging industry.

The road map is to be a guideline for the industry's development for five years, from 2008 to 2013. Having spent three months studying the overall status and market potential of RFID, the research team found four key potential areas for RFID development. They are the use of RFID in animal identification and food traceability, logistics, transport and the financial sector.

RFID can be used in animal identification and food traceability to identify livestock individually and trace the food products back through the supply chain to their origin, while logistics can use RFID in product delivery and inventory management. It also includes the use of RFID in wholesale and retail systems. In the transport sector, RFID will be used to facilitate fare and toll collections by mass-transit systems, manage fleets and support new intelligent transport systems while it can also be developed as an electronic purse by the financial sector.

Phaophak Siriruk, the associate dean of engineering at Mahanakorn University of Technology and an adviser for the road-map development project, said the road map had set these four areas as the direction research and development efforts should take. During the next five years, the plan also set a goal for increased use of RFID in animal identification and tracking as well as for food traceability within three years. Meanwhile it will encourage greater use of RFID in the country's logistics and supply-chain management in the next five years.

Phaophak said the road map would allow local researchers to have guidelines and see the overall picture to conduct local research on RFID development. It's also hoped that there will be at least 10 local RFID development projects conducted each year to serve industry.

For local development, the road map also identifies four areas of products and services that should be developed in the next five years under the CATS framework. CATS includes the development of chips, applications, terminals and systems. Under this framework, it's hoped to eventually turn Thailand into an RFID manufacturer instead of being solely a technology consumer.

Phaophak said the development of software applications and system services would offer strong potential as it would add more value to local developers. According to a market survey, the proportion of RFID hardware in the global market currently represents 59 per cent while software and system services combined had a 41-per-cent market share. However it's predicted that the growth of the latter two areas through until 2010 will increase to 42 per cent for software and 34 per cent for services while the growth of hardware will be only 28 per cent. These are also areas with potential for local RFID developers.

This year, it's expected that the worldwide RFID market will be worth US$5.3 billion (Bt180.2 billion), growing from $4.3 billion last year. The market value will continue to grow at around 30 to 35 per cent through to 2010, exceeding $7 billion.
In Thailand alone, it's estimated that the total RFID market in 2008 will reach Bt1.9 billion, increasing from Bt1.5 billion last year.

RFID is a new market, and Thailand has opportunities to take part. Phaophak said local developers therefore had to concern themselves with technology to be developed to serve industry's demands. Technology like Near Field Communication or NFC, for example, is also expected to play an important role in the RFID development area. As the concept emerges from the combination of contactless RFID and interconnection technologies, it can be used in mobile-phone devices to turn a tiny instrument into, for example, an access key, a ticket for public transport or even a purse to make a payment.

With an NFC chip embedded in their mobile phone, users can just tap the device on a reader and then use the phone as a means of authentication to access offices, rooms, cars or sport clubs, or as a ticket to take public transport as well as paying for products and services. This technology will bring true mobility to people's lives so various kinds of new applications and services can be developed to respond to the new emerging requirements.

To encourage the local RFID industry, the road map has also set a strategy to promote local development with the establishment of a centre to allow local developers and the private sector to use development tools at a lower cost. The plan also includes the development of a standard RFID platform which is open for the community to make further improvements.

NSTDA and six agencies install solar cells

NSTDA and six agencies install solar cells to increase access to education in remote areas


The National Science and Technology Development Agency (NSTDA) installed solar panels at 36 hill tribe learning centers that are part of a project by HRH Princess Sirindhorn to expand learning opportunities for schools in remote areas with no electricity. The NSTDA also joined six other agencies in a project to make sure that the solar cells will be well maintained and used efficiently to develop education in an integrated way.

The solar panels developed by the NSTDA are a hybrid between amorphous silicon technology and thin film silicon crystal technology. They produce three megawatts of power a year, or enough to power six 11-watt light bulbs for 12 hours a day and a 21-inch TV for one hour a day. They can also power a DVD player or satellite dish for educational use during the day time while storing power in a battery to use for evening classes for adults. They can also be used to power short wave radios and the community’s alarm system.

To make the project more complete, the NSTDA has also coordinated with six agencies that will help maintain and oversee use of the equipment after it is installed. The Basic Education Board and the Non-formal Education Management Office will check to see if the equipment is used efficiently. The Science and Technology Teaching Promotion Institute is preparing a course module about solar cells. The Department of Alternative Energy Development and Energy Conservation, the Industrial Technicians Vocational Education Office and King Mongkut’s Institute of Technoloogy, Thonburi, will all help maintain the solar cells and train the teachers and students how to maintain them.

The 36 learning centers that are under the care of HRH Princess Sirindhorn’s project consist of 17 centers in Tak Province, 17 in Chiang Mai Province, and 9 in Mae Hong Son Province. Now about half of the solar panels have been installed for a cost of Bht 100,000 per center. This is only half the cost of using imported equipment. The newly developed solar cells have a useful lifetime of up to 20 years.

NECTEC, Microsoft join to fight cyber crime

NECTEC, Microsoft join to fight cyber crime


The National Electronics and Computer Technology Center (NECTEC) signed an MOU with Microsoft (Thailand) Company Limited about a new Security Cooperation Program (SCP), a worldwide government sector initiative to build up a network for quick access to news about movements in the world of technology that will make data security monitoring more efficient in compliance with the 2007 Computer Fraud Act. Thailand is the second country in the Asia Pacific to sign this agreement after the Philippines.

The way the network works is that when there is a security breach in the system, Microsoft will send the information through its website and call center so the member agencies can analyze the danger, issue warnings, and find ways to control the threat in time before it escalates. Also, if any member agency discovers a loophole in the Microsoft platform then they must inform Microsoft so they can fix it.

Dr. Komain Pibulyarojana, Director of the Technology for Security Program, Thai Computer Emergency Response Team (ThaiCERT) at NECTEC, said the Security Cooperation Program (SCP) was a way to receive warnings directly from the data center in the US. ThaiCERT will be the first agency to be notified about new viruses or other infections before they spread through Europe and Asia. When they receive a warning, ThaiCERT will assess the danger level first before issuing a public warning.

Dr. Komain added that there are many kinds of internet crime. Danger is often hidden in new technology, so internet users have to watch it very closely. Now there is a campaign to let officials from government agencies receive training at Microsoft so that they can learn techniques and methods to deal with cyber crimes and control them before they get out of hand. The most worrisome thing for average internet users is the need to protect their personal information that is in the form of electronic data because there is a trend toward increasing data theft through phishing. Programmers can steal the personal data of internet users, and that may later cause many kinds of problems. This is a matter that needs to be seriously suppressed.

Biotechnology to conserve

Biotechnology to conserve the teak trees used to restore the Giant Swing


The Giant Swing is an ancient monument that has been a part of the history of Bangkok ever since it was founded in 1784. King Rama I ordered to have the large swing built for the annual swinging or Triyambawai ceremony. In 1949, the Fine Arts Department declared the Giant Swing a national historical monument.

In 2004 the Bangkok Metropolitan Administration and the Fine Arts Department agreed that the Giant Swing was in critical need of repair. They set about searching for suitable logs to serve as new pillars so that this important monument can continue to be a part of Bangkok. The search for perfectly straight trees that were the same size as the originals resulted in the discovery of six appropriate trees in Denchai District, Phrae Province. The first was found along Highway Number 101 in between Denchai and Sri Satchanalai. The second was found in the area of the Sai Yoi Forest Preservation Unit along the Denchai-Lampang highway and the final four trees were found in Huay Rai Forest in front of Wat Huay Rai in Denchai District.

The villagers in the places where the teak trees grew loved them and wanted to keep them but they agreed to donate them for the purpose of restoring the Giant Swing for the occasion of the 60th anniversary of His Majesty the King's Accession to the Throne. The Bangkok Metropolitan Administration joined the National Genetic Engineering and Biotechnology Center (BIOTEC), the Royal Forestry Department and the Natural Resources and Environment Ministry to initiate a project to propagate the trees that were used to restore the Giant Swing so that their lines could be carried on for everyone in the nation.

At BIOTEC, Dr. Somvong Trakoolrung, Director of the DNA Technology operations unit, inspected the DNA of the six trees, which were designated Primary Pillar 1, Primary Pillar 2, Secondary Pillar 1, Secondary Pillar 2, Secondary Pillar 3 and Secondary Pillar 4, and compared their DNA to that of other teak trees within a one-kilometer radius of where they grew.

Dr. Orawan Chatchawankanphanich, a researcher at the plant genetic engineering research unit at BIOTEC, used a tissue culture technique to propagate the trees used to make the Giant Swing, especially Primary Pillar 1, which was 90 years old, perfectly straight and was very resistant to insect damage. The objective of her project is to produce cloned saplings that could be planted out in nature.

BIOTEC is in the process of propagating the six Giant Swing trees to produce the first batch of 10,000 auspicious saplings within 2008, with the ultimate goal of producing 200,000 new trees by the end of 2010. The Royal Forestry Department will take the sprouts generated through tissue culture and further propagate them by cuttings to produce one million saplings. The young trees will be distributed to different agencies and organizations to give to the public to plant all over the country in 2011, when His Majesty the King will celebrate his 84th birthday.

That way, citizens all over the country will be able to take part in helping preserve these auspicious teak trees. Teak is also one of the kinds of trees that is numbered among the “Nine Lucky Trees” of traditional belief. Teak signifies dignity and honour. Thus, by planting these lucky trees people will not only be able to show their loyalty to His Majesty the King but will also be able to join in a significant event that cements national unity and binds people together all over the country. Planting trees will have both direct and indirect benefits for future generations.

NSTDA research highlights go on show at NAC 2008

NSTDA research highlights go on show at NAC 2008


• Royal visit scheduled for 24 March 2008

• Public can book at NAC 2008 up to 500 clone saplings from auspicious Giant Swing teak trees

• Visitors invited to meet with scientists to discuss commercialization of projects


Reports:

• Goal to file 110 patent applications in 2008
• Fast Forward plan results in 75% more patent applications in 2007
• 54 patents commercially developed
• Goal to get Thai rice experiment into space


Bangkok (20 March 2008) – Thailand's top science and technology organisation, the National Science and Technology Development Agency (NSTDA), today (20 March 2008) announced that it will showcase its research work conducted during the past year in partnership with many of the country’s universities and other research institutions under the Fast Forward plan at an open exhibition called NAC 2008.

The NAC 2008 exhibition will take place on 24-26 March 2008 at Thailand Science Park, Pathum Thani.

Up to 500 cloned saplings from the auspicious teak trees used to construct the Giant Swing will be available for booking for visitors to NAC 2008. The cloned saplings will be given to visitors in December 2008, by which time they will no longer need special nurturing.

Her Royal Highness Princess Maha Chakri Sirindhorn will inspect the exhibition on 24 March 2008. For more information please check www.nstda.or.th/nac2008/.

Associate Professor Dr. Sakarindr Bhumiratana, President of the NSTDA, said, "The NSTDA and the various centres under its supervision, including BIOTEC, MTEC, NECTEC, NANOTEC, and TMC, increased by 75% the number of patents filed for innovations in 2007, as compared to the previous year. This is the result of our 3-year Fast Forward plan kicked off in 2007. The Fast Forward plan aims to accelerate the pace of innovation in Thailand and to get Thai scientists directly involved in the needs of industry, agriculture, and healthcare.

"Close collaboration with many universities and other research institutions has been a key component for this sharp acceleration in the pace of innovation," he said.

According to Assoc Prof Sakarindr, in 2007, NSTDA filed 92 patents, compared to 52 in the previous year.

For 2008, he anticipates that NSTDA will file 110 patent applications. "Scientists from the NSTDA and other partner institutions are currently working on 1,070 projects, and 54 of them have had patents issued and been commercially developed," he said.

Areas of research that have been the most fruitful in the past year are software, microchips and electronics, generating 29 per cent of the patents; medicine and public health, generating 20 per cent of the patents; and agriculture, generating 20 per cent of the patents.

"We will keep driving the Fast Forward plan by increasing our collaboration network with different universities, ministries and research institutions. This collaborative model that puts the nation first, will help ensure that we continue to accelerate the pace of innovation in Thailand and strengthen our economy," said Assoc Prof Sakarindr.

Professor Dr Morakot Tanticharoen, Director of the National Genetic Engineering and Biotechnology Center (BIOTEC), and the chairman of NAC 2008, said, "NSTDA focuses on research that is directly relevant to the needs of agriculture, industry and medicine.

"At NAC 2008 we are exhibiting current research projects, as well as those that have already been brought to the stage of commercial development. We are also putting on show those with real potential for commercial development so that business people and investors will have a chance to meet with scientists and discuss their work.

"We want to encourage dialogue that will help researchers understand the needs of industry better as well as what the market demands. We welcome commercial discussions so that the work which the NSTDA has been doing in collaboration with universities and other research organisations can quickly be put to benefiting our country," she said.

Prof Dr Morakot said that among the highlights of the displays at NAC 2008 would be a model of a potential project to grow Thai rice in space, the development of nanocrystals to make solar cells, new technology to measure the quality of biodiesel, a project that identified the DNA of the Giant Swing trees, and some projects that have already been commercialized by the private sector such as 'Bedtime Milk' and dental implants.

NSTDA holds an exhibition every year to inform the public of its work and stimulate the exchange of scientific knowledge. In addition to the exhibits, there will be seminars, business meetings, and lab tours to encourage greater commercialization of the research.